Researchers at King Abdullah University of Science and Technology (KAUST) developed an innovative technology to extract lithium from seawater. This case study highlights the translation activities and collaborative efforts among the KAUST startup Lithium Infinity and key stakeholders in the Kingdom—including the Ministry of Industry and Mineral Resources, Ma’aden, Saudi Aramco, and KAUST. Together, they are advancing the use of this technology to extract battery-grade lithium from in-Kingdom resources such as oil-field produced water, with the broader goal of establishing a localized lithium supply chain in Saudi Arabia.